PON1

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Name:	paraoxonase 1
Symbol:	PON1
Version of Orphanet:	2023-06-22 14:14:43
Synonyms:	ESA arylesterase 1 esterase A
XREF(s):	Orphanet Reactome Ensembl Genatlas HGNC OMIM SwissProt
Created:	13 May 2019 - 01:01
Changed:	22 Jun 2023 - 16:14

Related Genetic Tests

• Movement Disorders (gene panel)

Related Diseases

• Amyotrophic lateral sclerosis

Related Gene Panels

• Movement Disorders - UGent
  Details

  Gene	% of coding sequence sufficiently covered to detect heterozygous mutations	Copy number variation	Comments
  AARS1	99.99	1
  ACTB	100.00	1
  ACTL6B	99.90	1
  ADAR	99.84	1
  ADCY5	99.98	1
  ADH1C	99.94	1
  AFG3L2	99.97	1
  ALDH5A1	96.19	1
  ANO3	99.98	1
  AP3D1	100.00	1
  AP4M1	99.98	1
  APTX	99.92	1
  ARSA	99.99	1
  ARV1	99.85	1
  ARX	95.36	1
  ATM	99.83	1
  ATP13A2	99.96	1
  ATP1A3	99.98	1
  ATP6AP2	99.55	1
  ATP7B	100.00	1
  ATP8A2	100.00	1
  ATXN2	99.88	1
  AUH	99.95	1
  BCAP31	99.95	1
  BCS1L	99.99	1
  C19ORF12	99.99	1
  CACNA1A	99.98	1
  CACNA1B	100.00	1
  CACNA1E	99.82	1
  CARS2	99.99	1
  CHCHD2	99.89	1
  CHMP2B	99.80	1
  CHRNA4	100.00	1
  CHRNB2	99.99	1
  CIZ1	99.94	1
  CLPB	99.97	1
  CNTNAP1	99.98	1
  COASY	99.98	1
  COL6A3	99.99	1
  COQ9	99.62	1
  COX10	99.99	1
  COX15	100.00	1
  CP	99.95	1
  CRAT	99.99	1
  CSF1R	99.92	1
  CTC1	100.00	1
  CYP27A1	100.00	1
  DCAF17	99.84	1
  DCTN1	99.98	1
  DDC	99.67	1
  DEGS1	99.99	1
  DHDDS	98.65	1
  DHX30	99.96	1
  DLAT	99.65	1
  DLD	99.89	1
  DMXL2	99.86	1
  DNAJC13	99.86	1
  DNAJC5	99.99	1
  DNAJC6	99.48	1
  DNAL4	99.89	1
  DRD3	100.00	1
  EARS2	99.96	1
  ECHS1	100.00	1
  EEF1A2	100.00	1
  EIF4G1	100.00	1
  EPRS1	99.53	1
  ETHE1	84.97	1
  FA2H	99.98	1
  FASTKD2	99.93	1
  FBXO7	99.98	1
  FITM2	99.99	1
  FOXG1	99.91	1
  FOXRED1	100.00	1
  FTL	99.99	1
  FUCA1	98.72	1
  FUS	99.93	1
  GABRB2	99.92	1
  GAMT	100.00	1
  GBA1	96.92	1
  GBE1	99.73	1
  GCDH	100.00	1
  GCH1	99.94	1
  GFAP	99.99	1
  GFM2	99.87	1
  GIGYF2	99.94	1
  GJC2	100.00	1
  GLB1	100.00	1
  GRID2	100.00	1
  GM2A	100.00	1
  GNAL	100.00	1
  GNAO1	99.86	1
  GNB1	100.00	1
  GPR88	100.00	1
  GRIN1	100.00	1
  GRIN2B	99.99	1
  GRN	100.00	1
  GSX2	100.00	1
  GTPBP2	99.98	1
  HEXA	99.99	1
  HIBCH	99.70	1
  HPRT1	97.80	1
  HSD17B10	99.98	1
  HTRA2	99.99	1
  HTT	99.98	1
  IFIH1	99.84	1
  IREB2	99.90	1
  IRF2BPL	99.21	1
  JAM2	91.82	1
  JPH3	100.00	1
  KCNA4	100.00	1
  KCNMA1	99.89	1
  KCNQ2	100.00	1
  KCTD17	100.00	1
  KMT2B	99.99	1
  LIPT1	99.89	1
  LIPT2	99.99	1
  LRP10	99.99	1
  LRPPRC	99.80	1
  LRRK2	99.44	1
  LYST	99.87	1
  MAPT	99.80	1
  MAT1A	99.70	1
  MCOLN1	100.00	1
  MDH2	99.54	1
  MECP2	99.95	1
  MECR	99.63	1
  MED20	99.99	1
  MICU1	99.56	1
  MMADHC	99.76	1
  MPV17	99.98	1
  MRE11	99.93	1
  MRPS34	100.00	1
  MYBPC1	99.77	1
  MYORG	99.99	1
  NAXD	99.99	1
  NDUFA1	99.93	1
  NDUFA10	99.98	1
  NDUFA12	99.21	1
  NDUFA9	100.00	1
  NDUFAF4	99.95	1
  NDUFAF6	99.86	1
  NDUFS1	99.79	1
  NDUFS3	100.00	1
  NDUFS7	99.99	1
  NDUFS8	100.00	1
  NHLRC2	99.83	1
  NKX2-1	100.00	1
  NKX6-2	100.00	1
  NPC1	99.99	1
  NPC2	100.00	1
  NTNG2	99.98	1
  NUP62	100.00	1
  PANK2	99.99	1
  PARK7	99.93	1
  PCCA	99.90	1
  PCCB	99.97	1
  PCDH12	100.00	1
  PCDH19	99.98	1
  PDE10A	87.37	1
  PDE8B	99.98	1
  PDGFB	99.99	1
  PDGFRB	99.99	1
  PDHA1	99.04	1
  PDHX	99.64	1
  PEAR1	99.89	1
  PEX16	99.94	1
  PINK1	99.69	1
  PLA2G6	99.98	1
  PLEKHG2	99.99	1
  PLP1	99.98	1
  PMPCB	99.94	1
  PNKD	100.00	1
  PNKP	100.00	1
  PNPLA8	99.92	1
  PNPT1	99.56	1
  PODXL	93.29	1
  POLG	100.00	1
  POLR3A	99.97	1
  PON1	99.70	1
  PRKN	99.99	1
  PRKRA	99.94	1
  PRNP	100.00	1
  PRRT2	99.97	1
  PTRHD1	100.00	1
  PTS	99.93	1
  QDPR	99.92	1
  RAB11B	100.00	1
  RAB39B	99.99	1
  RAD51	90.17	1
  RELN	99.98	1
  REPS1	99.93	1
  RHOBTB2	100.00	1
  RIC3	100.00	1
  RNF216	99.99	1
  SCN11A	99.94	1
  SCN4A	99.98	1
  SCN8A	99.77	1
  SCP2	94.94	1
  SDHA	99.98	1
  SDHAF1	99.99	1
  SDHD	82.93	1
  SEPSECS	99.78	1
  SERAC1	99.90	1
  SETX	99.97	1
  SGCE	93.12	1
  SLC18A2	100.00	1
  SLC19A3	99.95	1
  SLC20A2	99.95	1
  SLC25A42	99.99	1
  SLC2A1	99.93	1
  SLC30A10	99.99	1
  SLC30A9	99.75	1
  SLC39A14	92.87	1
  SLC44A1	99.90	1
  SLC6A3	99.96	1
  SLC6A8	99.99	1
  SMPD1	100.00	1
  SNCA	99.97	1
  SNCAIP	99.99	1
  SPG11	99.89	1
  SPR	99.99	1
  SQSTM1	100.00	1
  STUB1	99.99	1
  SUCLA2	99.96	1
  SUOX	100.00	1
  SURF1	100.00	1
  SYNJ1	99.91	1
  SYT1	99.70	1
  TAF1	99.84	1
  TANGO2	99.85	1
  TBC1D24	100.00	1
  TENM4	99.99	1
  TH	99.99	1
  THAP1	99.96	1
  TIMM8A	100.00	1
  TOR1A	100.00	1
  TPI1	99.95	1
  TPK1	99.96	1
  TRAK1	99.98	1
  TRAPPC11	99.93	1
  TRAPPC12	99.96	1
  TRIT1	99.25	1
  TSEN2	99.98	1
  TSFM	100.00	1
  TUBB4A	100.00	1
  TXN2	99.88	1
  UBA5	99.95	1
  UBTF	99.99	1
  UCHL1	99.99	1
  UFM1	99.25	1
  UGDH	99.77	1
  UQCRQ	99.96	1
  VAC14	99.91	1
  VAMP2	100.00	1
  VCP	99.99	1
  VPS13A	99.68	1
  VPS13C	99.65	1
  VPS13D	99.96	1
  VPS16	100.00	1
  VPS35	99.83	1
  WARS2	97.72	1
  WDR45	99.99	1
  WDR73	99.92	1
  XK	99.98	1
  XPR1	99.13	1
  YY1	100.00	1
  ZC4H2	99.98	1
  ZNF142	100.00	1