RANGRF | Belgian Genetic Tests database

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Name:	RAN guanine nucleotide release factor
Symbol:	RANGRF
Version of Orphanet:	2023-06-22 14:14:43
Synonyms:	HSPC165 HSPC236 MOG1 MOG1 homolog (S. cerevisiae) RANGNRF
XREF(s):	Orphanet Genatlas OMIM HGNC Reactome Ensembl SwissProt
Created:	13 May 2019 - 01:01
Changed:	22 Jun 2023 - 16:14

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Related Diseases

Related Gene Panels

Brugada syndrome (16 genes) - VUB

Details

Gene	% of coding sequence sufficiently covered to detect heterozygous mutations	Copy number variation	Comments
SCN5A
GPD1L
CACNA1C
CACNB2
KCNE3
SCN3B
HCN4
CACNA2D1
KCND3
KCNE5
KCNJ8
RANGRF
SLMAP
TRPM4
SCN2B
SCN1B

Cardiomyopathy, hereditary (208 genes) - VUB

Details

Gene	% of coding sequence sufficiently covered to detect heterozygous mutations	Comments
ABCC9	100.00	No comment
ACAD9	100.00	No comment
ACADVL	98.89	No comment
ACE	97.11	No comment
ACTA1	100.00	No comment
ACTC1	100.00	No comment
ACTN2	100.00	No comment
ADD3	100.00	No comment
ADRB2	100.00	No comment
AGXT	100.00	No comment
AGTR1	100.00	No comment
AKAP9	100.00	No comment
ALPK3	98.02	No comment
ANKRD1	100.00	No comment
APOA1	99.97	No comment
B2M	100.00	No comment
BAG3	100.00	No comment
BRAF	96.97	No comment
CACNA1C	100.00	No comment
CACNB2	100.00	No comment
CALM1	100.00	No comment
CALM2	100.00	No comment
CALM3	99.99	No comment
CALR3	100.00	No comment
CASQ2	100.00	No comment
CASZ1	95.56	No comment
CAV3	100.00	No comment
CAVIN4	100.00	No comment
CBL	100.00	No comment
CDH2	97.48	No comment
CHRM2	100.00	No comment
CMYA5	99.99	No comment
CNBP	100.00	No comment
COA5	100.00	No comment
COA6	100.00	No comment
COX10	100.00	No comment
COX15	100.00	No comment
CRYAB	100.00	No comment
CSRP3	100.00	No comment
CTF1	30.96	No comment
CTNNA3	100.00	No comment
DES	100.00	No comment
DLG1	100.00	No comment
DMD	100.00	No comment
DNAJC19	100.00	No comment
DNM1L	100.00	No comment
DOLK	100.00	No comment
DSC3	98.44	No comment
DSG2	99.61	No comment
DSP	100.00	No comment
DTNA	100.00	No comment
ECRG4	99.32	No comment
ELAC2	99.99	No comment
ELN	100.00	No comment
EMD	99.84	No comment
EYA4	100.00	No comment
FBXO32	100.00	No comment
CFH	100.00	No comment
FHL2	100.00	No comment
FHOD3	100.00	No comment
FKRP	98.68	No comment
FKTN	100.00	No comment
FLNC	100.00	No comment
FLT1	99.53	No comment
FOXD4	100.00	No comment
FXN	89.89	No comment
GAA	100.00	No comment
GATA4	80.69	No comment
GATA5	97.28	No comment
GATA6	81.11	No comment
GATAD1	88.18	No comment
GLA	100.00	No comment
GTPBP3	100.00	No comment
HACD1	95.46	No comment
HADHB	100.00	No comment
HAND1	100.00	No comment
HCN4	92.35	No comment
HIF1A	100.00	No comment
HRAS	100.00	No comment
HSPB6	99.65	No comment
HSPB7	100.00	No comment
ILK	100.00	No comment
INS-IGF2	99.94	No comment
ISL1	100.00	No comment
JPH2	95.10	No comment
JUP	100.00	No comment
KARS1	100.00	No comment
KAT2B	94.80	No comment
KCND2	100.00	No comment
KCNE1	100.00	No comment
KCNH2	94.44	No comment
KCNJ12	100.00	No comment
KCNQ1	91.07	No comment
KIF20A	100.00	No comment
KLF10	100.00	No comment
LAMA2	100.00	No comment
LAMA4	100.00	No comment
LAMP2	100.00	No comment
LDB3	100.00	No comment
LMNA	99.93	No comment
LRRC10	100.00	No comment
MAP2K1	100.00	No comment
MAP2K2	99.98	No comment
MIB1	100.00	No comment
MIB2	99.31	No comment
MRPL3	100.00	No comment
MRPL44	100.00	No comment
MTO1	95.75	No comment
MYBPC3	100.00	No comment
MYH15	100.00	No comment
MYH6	100.00	No comment
MYH7	100.00	No comment
MYH7B	99.96	No comment
MYL2	100.00	No comment
MYL3	100.00	No comment
MYLK2	100.00	No comment
MYO6	100.00	No comment
MYOM1	100.00	No comment
MYOM3	100.00	No comment
MYOZ1	100.00	No comment
MYOZ2	100.00	No comment
MYPN	100.00	No comment
NAA10	96.03	No comment
NCOA6	100.00	No comment
NDUFAF1	100.00	No comment
NDUFV2	100.00	No comment
NEB	99.99	No comment
NEBL	100.00	No comment
NEXN	100.00	No comment
NKX2-5	100.00	No comment
NPPA	100.00	No comment
NRAP	100.00	No comment
OBSCN	99.26	No comment
OBSL1	98.31	No comment
MED12	100.00	No comment
PDLIM3	100.00	No comment
PKP2	99.87	No comment
PLEC	99.82	No comment
PLEKHM2	99.60	No comment
PLN	100.00	No comment
PPCS	100.00	No comment
PRDM16	100.00	No comment
PRKAG2	95.88	No comment
PRNP	100.00	No comment
PSEN1	100.00	No comment
PSEN2	100.00	No comment
PTEN	98.86	No comment
PTPN11	98.80	No comment
RAF1	100.00	No comment
RANGRF	100.00	No comment
RBM20	99.82	No comment
RIT1	100.00	No comment
RPSA	97.87	No comment
RRAGC	99.99	No comment
RTKN2	100.00	No comment
RYR2	100.00	No comment
S100A1	100.00	No comment
SCN4B	100.00	No comment
SCN5A	100.00	No comment
SDHA	98.02	No comment
SGCB	94.58	No comment
SGCD	100.00	No comment
SGCG	100.00	No comment
SGK1	99.99	No comment
SHOC2	100.00	No comment
SLC12A1	100.00	No comment
SLC22A5	100.00	No comment
SLC25A3	100.00	No comment
SLC25A4	99.09	No comment
SMC1A	100.00	No comment
SNTA1	84.25	No comment
SOD2	100.00	No comment
SOS1	100.00	No comment
SYNE1	100.00	No comment
SYNE2	100.00	No comment
SYNM	92.59	No comment
TAF1A	100.00	No comment
TAX1BP3	100.00	No comment
WWTR1	99.81	No comment
TBX20	100.00	No comment
TBX5	100.00	No comment
TCAP	100.00	No comment
TCF21	100.00	No comment
TGFB3	100.00	No comment
TJP1	99.14	No comment
TK2	95.90	No comment
TMED4	100.00	No comment
TMEM43	100.00	No comment
TMEM87B	99.37	No comment
TMPO	99.87	No comment
TNNI3	100.00	No comment
TNNI3K	100.00	No comment
TNNT2	100.00	No comment
TNNT3	100.00	No comment
TPM1	99.98	No comment
TRIM54	99.66	No comment
TRIM55	100.00	No comment
TRIM63	100.00	No comment
TRPM4	100.00	No comment
TSFM	93.22	No comment
TTN	100.00	No comment
TTR	100.00	No comment
TXNRD2	96.90	No comment
VCL	100.00	No comment
VEGFA	98.73	No comment
YWHAE	98.69	No comment
ZBTB17	100.00	No comment

Primary Electrical disorders/Brugada syndrome (genepanel) - UZA

Details

Gene	% of coding sequence sufficiently covered to detect heterozygous mutations	Copy number variation	Comments
ABCB4	100.00	0
ABCC9	100.00	0
ACTN2	100.00	0
AKAP9	100.00	0
ANK2	100.00	0
CACNA1C	100.00	0
CACNA2D1	100.00	0
CACNB2	100.00	0
CALM1	100.00	0
CALM2	100.00	0
CALM3	100.00	0
CASQ2	100.00	0
CAV3	100.00	0
CTNNA3	100.00	0
DES	100.00	0
DPP6	100.00	0
DSC2	100.00	0
DSG2	100.00	0
DSP	100.00	0
GJA1	100.00	0
GJA5	100.00	0
GNB5	100.00	0
GPD1L	100.00	0
HCN4	100.00	0
JUP	100.00	0
KCNA5	100.00	0
KCND3	100.00	0
KCNE1	100.00	0
KCNE2	100.00	0
KCNE3	100.00	0
KCNE5	100.00	0
KCNH2	100.00	0
KCNJ2	100.00	0
KCNJ5	100.00	0
KCNJ8	100.00	0
KCNK17	100.00	0
KCNQ1	100.00	0
LMNA	100.00	0
NKX2-5	100.00	0
NOS1AP	100.00	0
NPPA	100.00	0
PKP2	100.00	0
PLN	100.00	0
PPA2	100.00	0
PRKAG2	100.00	0
RANGRF	100.00	0
RRAD	100.00	0
RYR2	100.00	0
SCN1B	100.00	0
SCN2B	100.00	0
SCN3B	100.00	0
SCN4B	100.00	0
SCN5A	100.00	0
SCN10A	100.00	0
SLMAP	100.00	0
SNTA1	100.00	0
TGFB3	100.00	0
TMEM43	100.00	0
TRDN	100.00	0
TRPM4	100.00	0
CDH2	100.00	0
CLCA2	100.00	0
FLNC	100.00	0
GNB2	100.00	0
MYL3	100.00	0
MYL4	100.00	0
RBM20	100.00	0
RNF207	100.00	0
SLC4A3	100.00	0
TANGO2	100.00	0
TECRL	100.00	0
TNNI3K	100.00	0
TTN	100.00	0

Primary cardiac arrhythmias (113 genes) - VUB

Details

Gene	% of coding sequence sufficiently covered to detect heterozygous mutations	Comments
ABCC9	100.00	No comment
ACTN2	100.00	No comment
ADRB1	78.34	No comment
ADRB2	100.00	No comment
AGTR1	100.00	No comment
AGXT2	100.00	No comment
AKAP9	100.00	No comment
ALG10B	100.00	No comment
ANK2	100.00	No comment
BAG3	100.00	No comment
CACNA1C	100.00	No comment
CACNA2D1	100.00	No comment
CACNA2D4	99.99	No comment
CACNB2	100.00	No comment
CALM1	100.00	No comment
CALM2	100.00	No comment
CALM3	99.99	No comment
CASQ2	100.00	No comment
CAV3	100.00	No comment
CIT	100.00	No comment
CKMT2	100.00	No comment
CRP	100.00	No comment
CSRP3	100.00	No comment
CTNNA3	100.00	No comment
DEPDC5	99.62	No comment
DPP6	96.95	No comment
DSC3	98.44	No comment
DSG2	99.61	No comment
DSP	100.00	No comment
EMD	99.84	No comment
FGF12	100.00	No comment
GATA4	80.69	No comment
GATA5	97.28	No comment
GATA6	81.11	No comment
GJA5	100.00	No comment
GPD1L	100.00	No comment
HCN4	92.35	No comment
HSPA1L	100.00	No comment
JPH2	95.10	No comment
JUP	100.00	No comment
KCNA5	100.00	No comment
KCNAB2	100.00	No comment
KCNB2	100.00	No comment
KCND3	100.00	No comment
KCNE1	100.00	No comment
KCNE2	100.00	No comment
KCNE3	100.00	No comment
KCNE4	100.00	No comment
KCNE5	94.02	No comment
KCNH2	94.44	No comment
KCNJ16	100.00	No comment
KCNJ2	100.00	No comment
KCNJ5	100.00	No comment
KCNJ8	100.00	No comment
KCNK17	100.00	No comment
KCNK3	95.81	No comment
KCNQ1	91.07	No comment
KCNT1	99.74	No comment
KIF21B	100.00	No comment
LMNA	99.93	No comment
MYBPC3	100.00	No comment
MYH6	100.00	No comment
MYH7	100.00	No comment
MYL4	100.00	No comment
NAA10	96.03	No comment
NKX2-5	100.00	No comment
NKX2-6	100.00	No comment
NOS1AP	100.00	No comment
NPPA	100.00	No comment
NUP155	100.00	No comment
NUP37	100.00	No comment
PI4KA	99.44	No comment
PIK3CG	100.00	No comment
PITX2	100.00	No comment
PKP2	99.87	No comment
PLN	100.00	No comment
PRRX1	100.00	No comment
RANGRF	100.00	No comment
RBM20	99.82	No comment
REM2	100.00	No comment
RIMS1	99.79	No comment
RNF207	99.91	No comment
RYR1	98.38	No comment
RYR2	100.00	No comment
SCN10A	100.00	No comment
SCN1B	94.12	No comment
SCN2B	100.00	No comment
SCN3B	100.00	No comment
SCN4A	100.00	No comment
SCN4B	100.00	No comment
SCN5A	100.00	No comment
SCNN1A	100.00	No comment
SDHAF3	100.00	No comment
SEMA3A	100.00	No comment
SHOX2	99.15	No comment
SIRT6	100.00	No comment
SLC2A5	99.60	No comment
SLC4A3	100.00	No comment
SLMAP	100.00	No comment
SNTA1	84.25	No comment
TBX5	100.00	No comment
TGFB2	100.00	No comment
DDR2	97.72	No comment
TNNI3	100.00	No comment
TPM1	99.98	No comment
TRDN	100.00	No comment
TRPM4	100.00	No comment
TTN	100.00	No comment
UBR4	99.99	No comment
UBR5	100.00	No comment
WDR26	100.00	No comment
XIRP1	100.00	No comment
ZC3HC1	100.00	No comment

cardiopathy panel - UGent

Details

Gene	% of coding sequence sufficiently covered to detect heterozygous mutations	Copy number variation
ABCC9	99.92	1
ACADVL	100.00	1
ACTA2	99.99	1
ACTC1	98.57	1
ACTN2	99.99	1
AGL	97.67	1
AKAP10	99.85	1
AKAP9	99.27	1
ALG10	100.00	1
ANK2	99.98	1
ANKRD1	99.57	1
ATP5F1E	100.00	1
BAG3	100.00	1
BRAF	99.78	1
CACNA1C	100.00	1
CACNA2D1	97.12	1
CACNB2	99.93	1
CALM1	99.86	1
CALM2	99.62	1
CALR3	99.91	1
CASQ2	94.39	1
CAV3	100.00	1
CBL	99.95	1
CFC1	21.93	1
CITED2	100.00	1
COA5	98.65	1
CRELD1	99.99	1
CRYAB	100.00	1
CSRP3	100.00	1
CTF1	100.00	1
CTNNA1	99.98	1
CTNNA3	99.96	1
DCHS1	100.00	1
DES	100.00	1
DMD	99.76	1
DMPK	99.93	1
DNM1L	99.40	1
DOLK	100.00	1
DPP6	99.99	1
DSC3	99.73	1
DSG2	99.96	1
DSP	100.00	1
DTNA	100.00	1
ELN	99.86	1
EMD	99.93	1
EYA4	99.96	1
FBN1	99.85	1
FBXO32	99.99	1
CFH	99.97	1
FHL2	100.00	1
FKRP	100.00	1
FKTN	99.94	1
FLNC	99.99	1
FOXRED1	100.00	1
FXN	99.96	1
GAA	100.00	1
GATA4	99.99	1
GATA5	100.00	1
GATA6	99.90	1
GATAD1	99.79	1
GDF1	100.00	1
GJA1	100.00	1
GJA5	100.00	1
GLA	99.90	1
GLB1	100.00	1
GPD1L	99.97	1
GUSB	95.07	1
HAND1	99.99	1
HCN4	100.00	1
HFE	100.00	1
HRAS	100.00	1
ILK	100.00	1
JAG1	100.00	1
JPH2	99.99	1
JUP	99.94	1
KCNA5	100.00	1
KCND3	99.98	1
KCNE1	87.07	1
KCNE2	99.99	1
KCNE3	100.00	1
KCNE5	99.97	1
KCNH2	99.99	1
KCNJ2	100.00	1
KCNJ5	99.99	1
KCNJ8	100.00	1
KCNQ1	100.00	1
KRAS	99.13	1
LAMA4	99.93	1
LAMP2	98.95	1
LDB3	99.91	1
LMNA	99.96	1
MAP2K1	99.98	1
MAP2K2	99.99	1
MED13L	99.99	1
MIB1	99.91	1
MRPL3	99.94	1
MYBPC3	99.98	1
MYH6	100.00	1
MYH7	99.99	1
MYL2	99.99	1
MYL3	99.99	1
MYLK2	100.00	1
MYOM1	99.98	1
MYOZ1	99.93	1
MYOZ2	99.99	1
MYPN	99.88	1
NEBL	99.86	1
NEXN	97.73	1
NKX2-5	99.75	1
NKX2-6	100.00	1
NOS1AP	99.91	1
NPPA	100.00	1
NRAS	99.66	1
PDLIM3	99.94	1
PKP2	94.27	1
PLN	99.97	1
PRKAG2	99.96	1
PSEN1	100.00	1
PSEN2	99.97	1
PTPN11	99.98	1
RAF1	99.97	1
RANGRF	100.00	1
RBM20	99.99	1
RYR2	99.94	1
SCN1B	99.98	1
SCN2B	100.00	1
SCN3B	100.00	1
SCN4B	100.00	1
SCN5A	100.00	1
SCO2	100.00	1
SDHA	99.98	1
SGCD	100.00	1
SHOC2	99.96	1
SLC25A3	99.79	1
SLMAP	99.55	1
SMAD3	99.99	1
SNTA1	99.99	1
SOD2	99.98	1
SOS1	99.68	1
SPRED1	99.99	1
SYNE1	99.95	1
SYNE2	99.95	1
TAFAZZIN	99.98	1
TBX1	99.95	1
TBX20	99.99	1
TCAP	100.00	1
TGFB2	99.87	1
TGFB3	100.00	1
TGFBR1	99.94	1
TGFBR2	99.98	1
TLL1	99.94	1
TMEM43	99.96	1
TMEM70	99.99	1
TMPO	99.81	1
TNNI3	100.00	1
TNNT2	99.87	1
TPM1	99.92	1
TRDN	99.80	1
TRIM63	99.96	1
TRPM4	99.99	1
TSFM	100.00	1
TTN	99.15	1
TTR	100.00	1
TXNRD2	99.97	1
VCL	99.76	1
XK	99.98	1
ZFPM2	100.00	1