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Hereditary Breast and Ovarian Cancer, HBOC (13 genes)

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Full name:
Hereditary Breast and Ovarian Cancer, HBOC (13 genes)
Test type:
Clinical
Test specialty:
Molecular Genetics
Test purpose:
Post-natal Diagnosis,
Predictive and Pre-symptomatic diagnosis
Specimen:
Peripheral (whole) blood on EDTA
Method category:
Sequence analysis: entire coding region
Deletion/duplication analysis
Method technique:
Next Generation Sequencing (NGS)
Laboratory:
Centre de Génétique Humaine - CHU Sart-Tilman
RIZIV code:
565552-565563
EQA:
  • 2015 Familial Breast/Ovarian Cancer (full version) EMQN
  • 2020 Hereditary Breast and Ovarian Cancer (panel testing) EMQN
  • 2022 Hereditary Breast and Ovarian Cancer (panel testing) EMQN
  • 2023 Hereditary Breast and Ovarian Cancer (panel testing) EMQN
Accreditation (ISO 15189):
2022-02-24 / 2026-02-23
Turnaround time (maximum):
2 - 3 months
Document(s):
Created:
23 Aug 2019 - 16:51
Changed:
16 Jan 2024 - 13:41
URL:
https://www.chu.ulg.ac.be/jcms/c2_24711429/fr/recherche-d-une-predisposition-he…
  • Breast cancer, hereditary (13 genes) - ULG
    Gene % of coding sequence sufficiently covered to detect heterozygous mutations Copy number variation Comments
    BRCA1 100.00 1 CNV assessed by MLPA
    BRCA2 100.00 1 CNV assessed by MLPA
    TP53 100.00 1 CNV assessed by MLPA (on demand)
    PALB2 100.00 0
    CHEK2 100.00 0
    BARD1 100.00 0
    ATM 100.00 0
    MLH1 100.00 1 CNV assessed by MLPA (on demand)
    MSH2 100.00 1 CNV assessed by MLPA (on demand)
    MSH6 100.00 1 CNV assessed by MLPA (on demand)
    BRIP1 100.00 0
    RAD51C 100.00 0
    RAD51D 100.00 0