Precursor B-cell acute lymphoblastic leukemia
Name: |
Precursor B-cell acute lymphoblastic leukemia
|
Description: |
A rare acute lymphoblastic leukemia characterized by infiltration of bone marrow and peripheral blood by small to medium-sized blast cells typically positive for the B-cell markers CD19, cCD79a, and cCD22. Predilection sites for extramedullary involvement are the central nervous system, lymph nodes, spleen, liver, and testes. Patients present with evidence of bone marrow failure (i. e. thrombocytopenia, anemia, and/or neutropenia) and variable leukocyte count, as well as lymphadenopathy, hepatomegaly, splenomegaly, bone pain, and arthralgias.
|
ORPHAcode: |
99860
|
Synonyms: |
B-ALL
Precursor B-cell acute lymphoblastic leukemia/lymphoma
Precursor B-cell acute lymphocytic leukemia
Precursor B-cell acute lymphocytic leukemia/lymphoma
|
XREF(s): | |
Analyte(s): | |
Created: |
13 May 2019 - 01:02
|
Changed: |
01 May 2022 - 06:55
|